Cell-by-cell dissection of gene expression and chromosomal interactions reveals consequences of nuclear reorganization.
The functional consequences of long-range nuclear reorganization were studied in a cell-by-cell analysis of gene expression and long-range chromosomal interactions in the Drosophila eye and eye imaginal disk.Position-effect variegation was used to stochastically perturb gene expression and probe nuclear reorganization.Variegating genes on rearrange